Piskel vs Blender

WPiskel is HTML5-based so it works in any modern browser.

Piskel includes onion skinning, exporting to sprite sheets or gifs, defining frame rate, and present live playback.

The downloadable version of Piskel (built with node-webkit) is available for Windows, Linux, and Mac OS X.

Piskel is licensed under Apache License, meaning that the user can use the software for any purpose.

It is also easy on the eyes.

Once you get the hang of it its a very powerful tool

... so you can instantly see the result while drawing tiles

It has enough tools to be powerful, but not too many to put off beginners.

With the click of a button you can create amazing shading.

Blender is licensed under the GPL. Some Blender modules such as the Cycles rendering engine are licensed under the Apache 2.0 license.

Blender provides a full rigging system, and automates animation by interpolating between keyframe positions.

Blender embeds Python 3, which can be used to write add-ons, tools, extend the interface, rig characters and automate tasks.

Blender runs the Cycles path tracing engine under the hood. Cycles is a very powerful rendering engine capable of full path tracing (light fall off, caustics, volumetrics). It is mostly compatible with OpenCL and CUDA rendering, and is implementing mycropolygon displacement features. The upcoming release has a viewport engine called EEVEE whereby you can see and interact with your work in render mode in real time!

Support lots of modern 3D formats including DAE and FBX - ideal for game developers.

Releases are made every ~3 months.

Blender's node-based compositor has comprehensive video sequencing and post-processing features.

Although Blender's 3d painting and sculpting tools (mostly painting) are not at par with specialized software like Substance Painter, ZBrush, or Mari, it is more than capable of getting most jobs done if the user takes the time to learn and understand it.

Good keyboard shortcuts for everything. Keep your left hand on the keyboard and your right hand on the mouse.

It offers a round solution (it covers many areas and professional fields) for a freelancer, for free, constantly updated, very polished, and allowing high quality results that clients do require. After some learning, it becomes very useful for professional work.

There's a huge community to help you get started immediately.

The trick with Blender is to get used to its usage philosophy, as it keeps consistent through all the application. Once you get it, every feature or addition is learnt naturally, almost effortlessly.

You don't have to switch between software when you want to do different things. Because modeling, sculpting, composting, video editing etc can all be done in blender.