When comparing PyxleOS vs PaintCAD 4Windows, the Slant community recommends PyxleOS for most people. In the question“What are the best pixel art / sprite editors?” PyxleOS is ranked 26th while PaintCAD 4Windows is ranked 28th. The most important reason people chose PyxleOS is:
The user interface has support for color themes that are both built-in and user-definable. The canvas transparency tile can also be modified to the user's liking.
Specs
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Pros
Pro Customizable UI
The user interface has support for color themes that are both built-in and user-definable. The canvas transparency tile can also be modified to the user's liking.
Pro Lightweight
The size of the .jar binary is a little less than 1 MB, making the application very lightweight.
Pro Includes a useful text editor
PyxleOS features a basic text editor module that can be used for note-taking or modifying a file that follows encoding standards.
Pro Secure, Java-based cross platform binary
PyxleOS can be used on any OS that runs Java 8 and above.
Pro Free and open source
The download of PyxleOS is free and all source code is available at a public repository at GitHub.
Pro Doesn't need to be installed
Simply download package, unpack, and use: no installation/setup/registry are required. Furthermore, all settings are saved in its own folder.
Pro You can draw images using the keyboard alone
The cursor on the image allows you to move it to any pixel of your image and place colored pixels precisely. You can draw on a small notebook (when travelling on a train or bus, for example), or in any other situation where you don't have access to a mouse.
Pro Completely free to use
All the user has to do is download the software and put it to use: draw images, create animations (gif), videos (avi), tilemaps, draw raster PCF fonts, and use it on your images for free!
Pro Support for Russian and English
The interface and help system have two localizations (English and Russian) included in the distributive package.
Pro Works with every Windows version
PaintCAD 4Windows doesn't need any .net, java, or other VM installed: it is a pure Windows 32-bit application and will work on every Windows-based operating system starting from Windows 95 until Windows 10.
Cons
Con Undo/redo unavailable
Undo/redo functions are not available in PyxleOS.
Con Lacks a number of features
Due to it being relatively new software, PyxleOS is somewhat buggy and underfeatured.