When comparing PyxleOS vs Paint.NET, the Slant community recommends Paint.NET for most people. In the question“What are the best pixel art / sprite editors?” Paint.NET is ranked 9th while PyxleOS is ranked 26th. The most important reason people chose Paint.NET is:
Unlike most photo editing software, Paint.NET is simple to learn and easy to use. This means less time is spent learning the in's and out's of Paint.NET and more time on photo editing. For those who only edit photos sporadically and don't have time to invest in learning complicated tools for editing, Paint.Net will suit your needs.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Customizable UI
The user interface has support for color themes that are both built-in and user-definable. The canvas transparency tile can also be modified to the user's liking.
Pro Lightweight
The size of the .jar binary is a little less than 1 MB, making the application very lightweight.
Pro Includes a useful text editor
PyxleOS features a basic text editor module that can be used for note-taking or modifying a file that follows encoding standards.
Pro Secure, Java-based cross platform binary
PyxleOS can be used on any OS that runs Java 8 and above.
Pro Free and open source
The download of PyxleOS is free and all source code is available at a public repository at GitHub.
Pro Easy to learn and use
Unlike most photo editing software, Paint.NET is simple to learn and easy to use. This means less time is spent learning the in's and out's of Paint.NET and more time on photo editing. For those who only edit photos sporadically and don't have time to invest in learning complicated tools for editing, Paint.Net will suit your needs.
Pro Free software
There is no charge for this software; but donations are welcomed.
Pro Lightweight
Paint.net provides a streamlined but effective core tool set. Support for advanced and niche features is provided through modular plugins, allowing the user to install only what's needed.
Pro Actively developed
The project is active and being continually expanded and refined.
Pro Active and friendly community
The forums are filled with tutorials, as well as people who are friendly and eager to help.
Pro Plugins allow extra functionality
Plugins can be made by anyone in the community, and are offered for download on the forum. They extend the capabilities of Paint.NET to cover most tasks.
Pro HiDPI support
Paint.NET supports fully HiDPI displays, with no scaling problems.
Cons
Con Undo/redo unavailable
Undo/redo functions are not available in PyxleOS.
Con Lacks a number of features
Due to it being relatively new software, PyxleOS is somewhat buggy and underfeatured.
Con Only available on Windows
Paint.NET is only available on Windows.
Con No project-based interface
You can only edit a single image at a time in Paint.NET. For example, in other tools you can open 5 or a 100 images at the same time, and stack those windows in all directions.
Furthermore, when you are editing in Paint.NET you can only "view" a single image at a time, even though you can have multiple images open. This limits your zooming ability, as the image will go fullscreen quite quickly, and hide parts of it behind the floating toolbars which can not be embedded anywhere on the screen.