When comparing MobaXterm vs VirtualBox w/ any Linux distro + Terminator, the Slant community recommends MobaXterm for most people. In the question“What are the best terminal emulators for Windows?” MobaXterm is ranked 6th while VirtualBox w/ any Linux distro + Terminator is ranked 31st. The most important reason people chose MobaXterm is:
MobaXterm can connect to practically anything.
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Pros
Pro Flexible
MobaXterm can connect to practically anything.
Pro X server support
In case you need X11 forwarding, MobaXterm has an integrated X server.

Pro Full linux subsystem with package manager
And you can install conda for additional package management.
Pro Tabbed or split mode
Multiple terminals can either be in tabs or split horizontally or vertically.

Pro Integral remote file editor
Edit remote files via ssh and sftp
Pro SSH tunnel controls and forwarding UI controls makes it easy
Pro Automatic SFTP
With MobaXterm, there's no fiddling with multiple apps: simply connect and everything is available.
Pro Connection manager
Pro ENV can use Windows PATH
Pro Password vault
Pro Server tools (HTTPD, SSHD, SFTPD, TTFT)

Pro Build in sftp file manager
Manipulate and edit remote files in the file browser.

Pro Integrates with WSL
Integrates perfectly with the Windows Subsystem for Linux. Out of the box it offers a shell to that system.
Pro Supports macro controls (multi commands in single screen)
Pro Runs Pre-configured virtual machines
Allows you to run your virtual machines pre-configured by you or others.
Virtual Box versions for:
-- Windows 7/8/10
-- All Linux installations
-- MAC OS x
-- Solaris 10/11
Virtual OSs include:
-- Oracle Linux 5/6/7.x (RHEL clones)
-- Solaris10/11
-- Occassionally a Windows Beta
Oracle itself provides many free VMs, pre-configured with various software stacks and hands-on lab materials for learning, geared toward. These have helped me earn three of my Oracle certifications:
-- Oracle Database development
-- Oracle DBA
-- MySQL development
-- Java Standard/Enterprise development
-- Big data
-- Webcenter portal & others
Pre-installed software in or more of the various stacks includes:
-- Oracle Database 11/12
-- JDK/Eclipse
-- Enterprise Mgr
-- MySQL
-- WebLogic
-- Cloudera, etc.

Pro Supports modern shells
Whether you prefer zsh, bash, or fish, Linux will support it.

Pro Isolated from Windows
VirtualBox provides almost total isolation from Windows running underneath it, removing a lot of security issues.

Pro Free / Libre Software
While the OS underneath it is proprietary and does spy on you or actively violate your freedom, so to speak, you can still have a little piece of mind knowing that VirtualBox (your Linux distro and shell of choice) as well as Terminator are all FOSS.
Cons
Con Not completely freeware
If you use MobaXterm at work, they hope you will pay for it. This isn't horrifying, but it's not providing any new features in Linux to warrant the outlay. Its integration with Putty in Windows as an X client may make it worth the funds.
Con Split screen prevents tabbed mode
If you split a screen within a tab, you have to go back to single screen before you can switch to another tab.
Con Can have some performance issues
MobaXterm can have some occasional performance issues. These happen rarely but it's worth mentioning that they exist, especially since this is a paid tool.
Con Install a whole operating system for one program
You would need to install the entire Linux distribution just for one single program.

Con Slightly slower than just running Linux
The Windows + VirtualBox layer introduces some overhead that wouldn't be present if Linux were installed directly on the machine.
