Here’s the Deal
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When comparing AutoPy vs PyAutoGUI, the Slant community recommends AutoPy for most people. In the question“What is the best GUI automation library?” AutoPy is ranked 1st while PyAutoGUI is ranked 2nd.
Ranked in these QuestionsQuestion Ranking
Common Questions
Pros
Pro Open source and cross-platform
Pro Support for image processing
Functions for finding colors, and working with bitmaps.
Pro Allows Mouse & Keyboard control
Pro Simple
Made to be used in Python in an intuitive and easy way.
Pro Efficient
It's a thin-wrapper of code written in pure C.
Pro Python package with few system dependencies
Requires scrot but else it's almost pure Python code.
Pro Cross-platform
Cons
No cons yet!
Con Only pixel-perfect image matching
When locating element by image comparison, it must be pixel perfect, meaning that any platform/machine change in the UI even very minor will break your script.