Reason vs Sequel 3

As of version 9.5, Reason now supports VSTs.

Synths, effects, and utilities can be modularly wired via audio and CV.

You can go really deep into creating sound and routing. Find possibilities you cant do with any other DAW.

Mulitple high quality built in synthesisers, drum loops, samplers and effects with plenty of pre-built patches to explore plus the ability to create your own unique sounds.

Reason's rack and mixer visually emulate real studio hardware through a skeuomorphic GUI/UX, allowing you to route audio cables and CV very intuitively. Hit "tab" on your computer keyboard, and you can see the rear of the rack, making routing very easy to understand.

Reason may look intimidating at first, but it is just as easy to learn as any DAW, if not more so, yet has incredible depth once you delve deeper, with some options that are just not possible in other DAWs.

The multi fx are very nice. Great for transitions and complete sound management.

Reason makes it easy to stretch audio or slice it up for glitchy sound effects. When audio is loaded, it is analyzed so slice markers can be placed at the beginning and end of each note. Slice markers appear when the audio sample is double clicked.

Professionally produced tutorial videos often released by Propellerhead that show you how to use the software. Reason also has a thriving user base that offers video tutorials showing you how to do almost anything you need.

Using clips makes it very easy to automate precisely.

REX files record effects and slices on top of the original file, and will play audio at the tempo of a project. REX files provide many uses and are a great addition to Reason.

Reason's Audio Pitch Editor easily can hold its own to Melodyne Essentials. Makes editing vocals and other monophonic sound very easy.

MIDI out is a new addition in Reason, allowing feedback to MIDI devices.

Sequel 3 was made by the folks behind Cubase, and it is meant to be lighter and easier to learn. This program's focus on loops and computer generated drum patterns makes the process easier for people with no music knowledge.

There is a page exclusively meant for generating drum patterns.