When comparing Slax vs Red Hat Enterprise Linux, the Slant community recommends Slax for most people. In the question“What are the best Linux distributions for misanthropes?” Slax is ranked 62nd while Red Hat Enterprise Linux is ranked 115th. The most important reason people chose Slax is:
Changes you make in the configuration persist if you run from USB.
Specs
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Pros
Pro Persistent changes
Changes you make in the configuration persist if you run from USB.
Pro Pretty fast to boot up
It was considerably fast to turn on when booting from cd.

Pro Modules
Standard tar archives plus some simple shell scripting produces modules that you can load dynamically into the OS for added apps and functionality.
Pro Modern desktop

Pro Small footprint
About 200mb, but with a full KDE4 environment and loads of useful apps.
Pro Each version is supported for a really long time
Each released version of RHEL is supported for around ten years by Red Hat with constant bug fixes and security updates.
Pro Greatly favours stability over anything else
RHEL favours stability over being up-to date. For this reason it ships with packages that may be up to two years behind in order to ensure stability over everything else.
Using older versions for packages means that they have been thoroughly tested and used in production for quite some time, and are ensured to play well with each-other.
This strategy has paid off quite a lot in the past. One example is the Heartbleed bug which left RHEL unaffected since it was using a two-year old OpenSSL library which did not have the bug.
Pro Rapid security updates
Pro Built-in disaster recovery solutions through clusters
RHEL has several built-in solutions for disaster recovery. For example, it comes with pacemaker which can be configured to manage multi-site and and stretch clusters across multiple geographical locations for disaster recovery and scalability. It can also be configured to trigger notifications when the status of a managed cluster changes by using enhanced pacemaker alerts.
Pro Applications don't have to take into account potentially breaking changes in libraries
Since RHEL backports all updates and bug fixes to older versions in order to maintain package compatibility across releases, applications hosted on Red Hat Linux don't have to worry about potential breaking changes in libraries they use, especially language libraries.
Pro Best support as far as hardware goes
This distro is by far the one with the largest number of certified server-class hardware.
Pro Built-in support for containers
Comes with built-in management tools for containers (Atomic CLI, Cockpit) and a container runtime in the form of Docker engine.
Cons
Con Overly complicated HDD/SSD installation
While it has a nice layout Slax's lack of an installer tool like Tinycore's just can't be justified. It seems strange that it comes built in with programs that some users may not want, yet it doesn't have an easy way to install it. Due to its heavier use of RAM, built in software, and lack of an installer its hard to choose it over TC.
Con Works slowly on old computers
Con Infrequent releases
Since Slax is maintained by only one person, releases are not that frequent. So it may take a while to get bug fixes or new features once you start using it.
Con You need to buy a license
RHEL is a commercial Linux distributions and it's rather expensive as well, the cheapest license costs $349.
