When comparing Anima2D vs Marionette Studio, the Slant community recommends Anima2D for most people. In the question“What are the best 2D skeletal animation tools?” Anima2D is ranked 4th while Marionette Studio is ranked 11th. The most important reason people chose Anima2D is:
Everything you could want from a skeletal animation system, free and because purchased by unity promises to be native in future.
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Pros
Pro Purchased by unity
Everything you could want from a skeletal animation system, free and because purchased by unity promises to be native in future.
Pro Free
Pro Spring bones
Much like spring joints native to unity, you can set bones to have dynamic spring animations based on their parents.
Pro Actively maintained
Marionette Studio team is actively involved in the development of this software. There is a changelog available and a public Trello board.
Pro Cloud based solution
Projects and files can be stored in cloud and the is no need for creating backups.
Pro Animation export
Animations can be exported as image packs and using some 3rd party tools can be imported and used in Unity.
Pro Easy to use
Can be used by anyone - intuitive interface and short learning curve.
Pro Web-based software
Easy to be accessed as no software needs to be download or installed on your computer.
Cons
Con No longer supported by Unity.
This has been merged into the 2D Animation package.
Con Uses the Unity hierarchy
It's impossible to rename your asset after making your animation, otherwise you lose dependencies.
Con It's not free
Con No integration for major game development engines
There is no integration with major game engines such as Unity, Construct 2D, Unreal, Cocos 2dx, etc.