When comparing uScript + Unity3D vs Nez, the Slant community recommends Nez for most people. In the question“What are the best 2D game engines?” Nez is ranked 89th while uScript + Unity3D is ranked 97th. The most important reason people chose Nez is:
The community is very active, so if you ask for help you'll get it relatively quickly.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Automatically generates nodes for third-party script assets
uScript's nodes are a visual representation of actual code blocks, and it takes advantage of C#'s reflection capabilities to automatically create nodes for any scripts it finds in your project, regardless of the source. This makes it inherently compatible with pretty much everything.
Custom nodes can also be created by hand, for cases where the automatically created ones contain more elements than they actually need.
Pro Versatile flow diagram script model
Modeled after UDK's Kismet (the predecessor to UE4's Blueprint), uScript's scripts resemble flowcharts where each box represents a function or value, with connections between them representing program flow. This provides a better at-a-glance indication of game logic than a simple list of events, and makes complex behaviors easier to accomplish.
Pro Generates C# source code
Nodes are translated directly to C# files in your project. This is great for learning to code, and also for advanced users who can use uScript for fast prototyping and then further optimize the scripts if necessary.
Pro Active community
The community is very active, so if you ask for help you'll get it relatively quickly.
Pro Open source
Completely free, no need to pay for licenses.
Pro Cross-platform development thanks to the use of mono and xamarin
Nez is built on top of monoGame and can be used the make games for many platforms (Windows, Linux, Mac, Android or IOS).
Cons
Con Not that easy to use
It's a lot more complicated compared to something like Playmaker. Same tasks take a lot more time.
Con Just a framework
Meaning there's no visual scene designer so you'll have to write your own.