When comparing uScript + Unity3D vs OpenBOR, the Slant community recommends uScript + Unity3D for most people. In the question“What are the best game engines for beginners and non-programmers?” uScript + Unity3D is ranked 25th while OpenBOR is ranked 33rd. The most important reason people chose uScript + Unity3D is:
uScript's nodes are a visual representation of actual code blocks, and it takes advantage of C#'s reflection capabilities to automatically create nodes for any scripts it finds in your project, regardless of the source. This makes it inherently compatible with pretty much everything. Custom nodes can also be created by hand, for cases where the automatically created ones contain more elements than they actually need.
Specs
Ranked in these QuestionsQuestion Ranking
Pros

Pro Automatically generates nodes for third-party script assets
uScript's nodes are a visual representation of actual code blocks, and it takes advantage of C#'s reflection capabilities to automatically create nodes for any scripts it finds in your project, regardless of the source. This makes it inherently compatible with pretty much everything.
Custom nodes can also be created by hand, for cases where the automatically created ones contain more elements than they actually need.

Pro Versatile flow diagram script model
Modeled after UDK's Kismet (the predecessor to UE4's Blueprint), uScript's scripts resemble flowcharts where each box represents a function or value, with connections between them representing program flow. This provides a better at-a-glance indication of game logic than a simple list of events, and makes complex behaviors easier to accomplish.

Pro Generates C# source code
Nodes are translated directly to C# files in your project. This is great for learning to code, and also for advanced users who can use uScript for fast prototyping and then further optimize the scripts if necessary.
Pro With a bit of tweaking, it's also possible to create a platformer
It's possible for a non-programmer who is comfortable with text-based designing to tweak the engine in order to create a platformer. Almost all the parameters needed can be found in the OpenBOR wiki, so it's easy to find anything a new developer needs.

Pro Great genre-specific engine
OpenBOR can quickly help create a good Beat-Em-Up game without programming.
Pro Great, supportive community
OpenBOR community is highly active and very helpful.
Cons

Con Not that easy to use
It's a lot more complicated compared to something like Playmaker. Same tasks take a lot more time.
Con Text-based parametric editing
Heavy reliance on text-editing. No visual editor to edit characters and levels (although there are a few community-built ones that do the job).
