When comparing Guayadeque vs gmusicbrowser, the Slant community recommends Guayadeque for most people. In the question“What are the best audio players for UNIX-like systems?” Guayadeque is ranked 17th while gmusicbrowser is ranked 19th. The most important reason people chose Guayadeque is:
Most other players start rather slowly. This one is written in C++, and the end result is excellent speed.
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Pros
Pro Starts fast
Most other players start rather slowly. This one is written in C++, and the end result is excellent speed.
Pro Doesn't use much memory
Once installed, Guyadeque only uses about 15 MBs.
Pro Well-implemented auto playlist
After music has finished playing, Guadayeque will play a similar type of music.
Pro Handles large music databases very well
Pro Smart play
It automatically make a playlist song-by-song you hear from your music file. It finds similar songs. So, as you listen to a song an endless playlist with similar songs is about to happen..
Pro Lots of niceties / options / integration
Last.fm shows your profile in the software and also displays info about the artist.
Lyrics are downloaded automatically when you want to see them.
Cross-fading between songs keeps music constantly coming, which is very important when using music to block out ambient sounds.
VU (volume unit) Meters give you something to look at while the music is playing.
Pro Clean appearance
Guayadeque has a clean yet customizable appearance.
Pro Great with large libraries
This program uses a tagging system to help you find the music you're looking for, and can even help find duplicates. It will also automatically sync with a folder, meaning you don't have to manually initiate a scan.
Pro Cool AutoTagger
The smartest auto tagger out there. It has an intelligent regular expression system to tag the files based on the filename contents. If the name contains something like Band -Album - Track -Title www.download.mp3, the system lets you filter the metadata fields.
Pro Large assortment of layouts
You can pretty much emulate your favorite media player layout inside of gmusicbrowser as it has a large assortment of pre-made layouts as well as an insurmountable amount of options for custom layouts.
Pro Remembers playing/pause status even after restart
With most other options, you have to start the player, wait a few seconds, then click Play. Gmusicbrowser spares you the wait and plays music automatically upon startup (if you were playing music when you closed it previously).
Pro Intelligent auto playlists
Automatically generated playlists with the criteria you decide. Great for big collections.
Cons
Con Development seems to stall since 2016
Con Sidebar lists multiple artists as one artist
A song with multiple artists labeled like "Artist 1; Artist 2; Artist 3" will not be displayed under all three artists, but rather under an artist labeled as "Artist 1; Artist 2; Artist 3." This makes actions as simple as queuing up an album with multiple artists a huge pain.
Con Songs with differing artists in an album are displayed as separate albums
Suppose Album 1 by Album Artist A has a lot of songs by Artist A, with one song that features Artist B. Album 1 will get fractured across different artists in the sidebar.
Con Interface is too busy
There's a lot shown on each of Guayeque's screens, and the more important buttons (play/pause and skip buttons) are small and hidden in the top left corner. Most users use music players in the background, meaning they will be switching back and forth with whatever else they're doing. As such, having larger buttons in a more prime location would be preferable.
Con Sometimes freezes and crashes
This can happen if you change some settings i.e. add or remove tabs etc.
Con It won't install on Linux Mint 21
Con Held back by performance issues
Can be very slow, uses a lot of resources, and has a decent amount of lag when going between songs.
Con Doesn't support media keys
Con Unusual keyboard shortcuts
Space does not pause, for instance. This would have been useful, as hitting the space bar is easier than finding the play/pause button - most music players use the space bar in this fashion.
Con Some plugins are outdated
Several plugins works on older versions of libraries no longer available for recent distros.

Con Poor library management
Initial load may have issue skipping parts of ones library, re-scanning may not resolved the issue. It also may tax ones CPU quite a lot, during these load attempts.
Con No WMA support
For those with older libraries that may still have unconverted WMA files, this can be a non-starter.
Con Large assortment of features and layouts may be confusing
Some people may find all of gmusicbrowsers layout and options daunting to figure out.
