When comparing Keynote vs Origami, the Slant community recommends Origami for most people. In the question“What are the best tools for prototyping mobile interactions/animations?” Origami is ranked 3rd while Keynote is ranked 7th. The most important reason people chose Origami is:
Origami is offered to the public completely free, no monthly plans, no upfront cost whatsoever.
Specs
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Pros
Pro Imports nearly every type of asset
Can import all kinds of assets (images, videos, PDFs, sounds) into mockup without hassle.
Pro Animations and transitions
Keynote currently is one of the very few tools that supports animation of elements and transition of views without programming.
Pro Text Styles makes it easy to create typography systems
Pro Smart Snaps
Keynote has alignment grids (aka snap to grid feature) that snaps to end, midpoints, baselines etc of objects and grids. They are super useful when you want to follow a structured layout for your wireframe.
Pro Completely free
Origami is offered to the public completely free, no monthly plans, no upfront cost whatsoever.
Pro Powerful animations and interactions
Origami was actually built to help Facebook designers work on Paper, one of Facebook's latest apps. Every animation that is coded into Origami was first made for Paper. It uses powerful 3D effects and some of the most advanced features for scrolling, tapping and swiping to create a faithful and interactive prototype.
Pro Native testing
Developers can develop their prototypes with origami through their desktops, but the testing itself is done on the native devices.
Pro No code required
Origami is built by designers for designers. As such, it allows for quick prototyping without writing a single line of code.
Pro Open source
Origami is free and open source and it is hosted on GitHub.
Pro Like only-Mac-integration! Great app! Thank you.
Cons
Con Only available on Mac and it's file are not compatible with Microsoft Windows
Con Steep learning curve
Origami is a toolkit for Quartz Composer, and unfortunately the learning curve for it is quite steep. Especially for beginners.
Con Mac only
Since Origami is not an app in and on itself, but a plugin for Quartz Composer, which is built by Apple. Therefore, Origami is only available for Mac and for a developer to download and use it, they need to register as an Apple Developer.
Con Mouse driven interactions
There's no way to directly test the tactile interface.