What are the best Linux distributions?

Unity is awesome and user-friendly at many places. But it's not customizable at much extent. Getting rid of it can be either not possible or very problematic. Same is true about other Ubuntu-specific software. A lot of things don't work as expected. Even though the repository is based on Debian, some ways to do stuff don't actually work. It's better usually to use GUI whenever possible, than to manually edit files. This is frustrating.