Ranked in these QuestionsQuestion Ranking
Pro Well Tested and used by Gmail and Google Docs
Closure Templates being a project created by Google, is extensively used in some of the world's most famous and largest web apps which include Gmail and Google Docs. What this means for you is that you'll be using a Template engine that has not only been intensively tested but also that you'll be in good company, with lots of technical support.
Pro Language independent
Closure has been designed keeping most security risks in mind. Templates created using Closure are auto-escaped automatically. Hence you won't have to worry about any XSS attacks.
Pro High Performance
Closure templates do not tend to slow down your site's performance or increase your page load time. They're compiled to extremely efficient JS code so that your page renders extremely fast, whether the templating is done on the client end or the server end.
Con Not widely used outside of Google
Closure Templates are mostly used in projects developed by Google and not in projects by third-parties. As such, it's unlikely for further versions to be released or for changes to be merged.