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PSequel is currently free to use.
Pro Fast, native UI
The UI is clean, simple and elegant
Con Still in development, lack of some features
You can't add table with GUI yet, you need to write a statement
Con No way to save files
You cannot save a file. Makes it way to easy to lose work.
Con Closed source
PSequel is currently closed source and the developer has stated there is no plans to open source it in the near future.