There are many refactoring options including renaming and changing signature across entire projects. It also includes the an ability to preview changes before committing and exclude anything unwanted.

Pro
Excellent debugger

PyCharm can leverage run-time information when running your application with the built-in debugger to figure out what types can possibly be passed to which functions, etc.

Pro
Framework support

PyCharm supports cefpython and electron.js (with c bindings).

Pro
Pro features Free for students

JetBrains offers a Student Pack, which gives you a student license and access to the pro features of selected products such as PyCharm, IntelliJ IDEA and Php Storm.

Cons

Con
Memory-hungry

Can use a lot of memory (several GBs), especially when dealing with large projects.

Con
Can sometimes become very slow, freeze, and become unresponsive

It becomes extremely frustrating when you have to wait for the text you've typed to appear in your editor. Furthermore, during these freezes the editor does not always queue what your're typing, so you might have to wait > 15 seconds before you can continue your editing. This quickly affects the concentration of a developer, causing flow interruption and general performance degradation.