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Pros
Pro Web2py apps run on GAE, AWS, VPNs, PythonAnywhere, etc
Web2py apps are designed to be portable. With some minor restrictions web2py apps can run on any VPS on SQL databases and/or Mongo, as well as on Google App Engine with the Google Datastore. It is truly code ones and run everywhere. For example at Camio.com we use web2py internally to access a GAE datastore which contains more images than Instagram.
Pro Easy to learn without losing any power
web2py is very easy to learn for beginners, yet it has a great deal of power and flexibility as application needs become more complex. It includes an impressively comprehensive set of features, making development very productive without the need to integrate a lot of third-party libraries.
Pro Documentation is written in form of a book which is good for beginners
web2py documentation does not follow the common pattern of using Sphinx, MkDocs or ReadTheDocs which is goos for exeperienced developers. Although documentation in form of a book is very easy and good for beginners. Turning web2py the most easy and comprehensive framework to learn and also to teach.