When comparing Tessel 2 vs ESPRESSObin, the Slant community recommends ESPRESSObin for most people. In the question“What are the best single-board computers?” ESPRESSObin is ranked 31st while Tessel 2 is ranked 35th.
Ranked in these QuestionsQuestion Ranking
Pro NodeJS support out of the box
Out of the box it supports Node 4.x LTS and doesn't require any setup to use it.
Pro Co-processor system
Runs Linux and user application code on a 580MHz Mediatek router-on-a-chip, with an asynchronous 48MHz SAMD21 coprocessor for GPIO, ADC, I2C, SPI, PWM and UART programming
Pro Programmable via USB or Wifi
Pro Easy to get started with
The Tessel 2's "Getting Started" experience requires little more than installing Node.js and a single package (the CLI) via npm. Complete walkthroughs for Linux, Mac and Windows are available and up-to-date
Pro Fast SATA III port
Pro Das U-Boot bootloader
It uses the opensource boot loader "Das U-Boot".
Pro 3x Gigabit LAN
It has three Gb ethernet ports.
Pro Mini-PCI-E slot
Few SOC boards have this feature--and there are a couple Mini-PCIE RAID cards on the market that might work nicely
Con Very little memory
64 megabytes of RAM. This places it more in line with an Arduino style board than a SBC on the level of Raspberry Pi.