When comparing Webflow vs Adobe XD, the Slant community recommends Adobe XD for most people. In the question“What are the best high-fidelity website design tools?” Adobe XD is ranked 7th while Webflow is ranked 8th. The most important reason people chose Adobe XD is:
It's easy to be productive immediately with XD but it also includes a demo so that you can learn about some of the more powerful features.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Best in it's class
Speed & Quality webdesign done in your browser.

Pro Semi-collaborative development support
Webflow allows workload to be shared among multiple users. However, you can't leave comments for them.
Pro W3C-compliant HTML5/CSS3
Webflow generates W3C-compliant markup and stylesheets.
Pro Responsive web design with Bootstrap
Because it's based on Bootstrap, it works across all modern browsers & devices.
Pro Easy to use interface
It's easy to be productive immediately with XD but it also includes a demo so that you can learn about some of the more powerful features.
Pro Cross platform
It's available on both macOS and Windows.
Pro Repeat grid is a timesaver
Creating a list of items is simple with "repeat grid." Just create one and use repeat grid to duplicate that item vertically or horizontally. Then drag and drop text or images to create unique entries for each repeated item.
Pro UI Kits are available for iOS, Material Design, and more
Includes:
- iOS
- Google Material Design
- Windows UWP
- Wireframes
Pro Share online and gather feedback
Allows mockups to be pushed to the web where collaborators can try the mockup and leave feedback.
Pro Interactive mockups
XD allows you to wire any object to any destination page so that clicking a button asset will take you to a page that you specify.
Mockups can also simulate a scrolling page or window.
Cons

Con Based on Bootstrap
Bootstrap is rather old technology
Con Design tool is web-based, not a proper application.
The site doesn't state this explicitly.
Con Can't export your site for deployment unless you pay.
Not unreasonable, but something users should know before investing their time.
Con Uses JavaScript
Webflow uses JavaScript on its websites. Website visitors can have JavaScript disabled and be unwilling to enable it for the website they want to view, which would put a website created with Webflow out of their reach.

Con No way to collaborate on designs with comments
Forum post here.

Con No version control
Forum post here.
Con Fixed media queries
Webflow has four fixed breakpoints (desktop, laptop, mobile landscape & mobile portrait). The inability to set your own media queries can be limiting. If your layout breaks outside of these four options, you have to export the code and write them yourself.
Con No tools for animation
It is possible to create transitions, but this feature is very limited.
Con Only good for mockups
XD is not a multi-purpose tool like Sketch. It is not a good tool for logos, icons, or other design assets.
