When comparing ENIGMA Development Environment vs Gosu, the Slant community recommends Gosu for most people. In the question“What are the best 2D game engines?” Gosu is ranked 50th while ENIGMA Development Environment is ranked 60th. The most important reason people chose Gosu is:
Gosu is not a game development framework, only a media library that happens to be suited to game development. (Kind of like SDL in the C world.) That means the interface is relatively small.
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Pros
Pro Raw C++ power and GML accessibility
Almost full support for GML,
The ability to create and access C++ types, templates, and functions, compile DLLs and other C/C++ scripts
Pro Cross platform
Support for Windows, Mac and Linux.
Pro Compatible with GameMaker
Enigma can support over 90% of gamemaker's GML language
Pro Friendly user interface
besides the powerful combination between GML and C++, beginners can also use drag and dropping.
Pro Free and Open Source

Pro Faster than GameMaker
Written in C++, many features have been demonstrated running much faster than interpreted equivalents in GameMaker (up to 10-20 times faster than GM 8.1).
Pro Under active development
Changes are made daily to add new functions/fixing bugs.
Pro Helpful error messages
A full stack trace with available cores and memory information as well as operating system and Java version including file names and number is generated whenever an exception is encountered, with a handy link to submit the issue to GitHub.
Pro Lightweight
Gosu is not a game development framework, only a media library that happens to be suited to game development. (Kind of like SDL in the C world.) That means the interface is relatively small.
Pro Mature API, actively maintained and developed
Gosu has been under development since 2001. It is mature and has several toolkits built on top of it to provide additional functionality.

Pro Cross-platform, even mobile, using Ruby
Cons
Con A few bugs & glitches
Because Enigma is under very rapid development, with new functions added almost daily, some bugs and unexaplainable glitches can happen, though they also gets patched quickly.
Con No code refactoring
Like any C++ based programs, the ability to refactor is limited. However, the new Ide for engima will support a few refactoring cababilities
Con Deploying Ruby apps is a mess
Games built with the Ruby to .exe "compiler" do nothing more than extract your source code and Ruby.exe to %TEMP%, then run it. The code is not really compiled at all. The process for wrapping games as Mac apps is a bit nicer, but you'll need a paid Apple Developer subscription to code sign the app, or users will see a warning/error when running your game.
The only way to really compile Ruby is to use RubyMotion, which does not work on Windows and requires a paid subscription on top of the Apple Developer one.
(This Con is not specific to Gosu. Deploying Ruby code has never been fun.)
