When comparing BlitzMax vs PlayMaker + Unity3D, the Slant community recommends BlitzMax for most people. In the question“What are the best 2D game engines?” BlitzMax is ranked 52nd while PlayMaker + Unity3D is ranked 77th. The most important reason people chose BlitzMax is:
You can compile on Windows, Mac and Linux. Nothing to change. There are solutions to compile on the same machine for 2 targets.
Specs
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Pros
Pro Multi target
You can compile on Windows, Mac and Linux. Nothing to change. There are solutions to compile on the same machine for 2 targets.
Pro Modular
There are many modules to extend the features of the language: you can create PDF (via a Cairo module), or just download/upload files (via LibCurl), playing streaming sound (via BASS) and so on (databases, xml, xls...) User can create their own module (they could be written in plain BlitzMax)
Pro Easy syntax
Based on BASIC syntax. Supports OOP, collections (array, list and map)
Pro Stable language and source code
After many years the language it self is very stable. The packages contains the source code of ALL modules (excluding the source of the compiler).
Pro Easy to start, high productivity
BlitzMax is just ready after the installation. Open the IDE, write your code and just press F5 to see the results. You don't need to install other things to use the language. Of course if you want to change the language itself - or modules - you need to install MinGW or other libs, but guidelines are provided and easy to follow.
Pro Fast compiler
With comparison to the some of the other languages Blitzmax compiles source files fast enough.
Pro Compiles to native code
Good performance thanks to native code on each of the target platforms.
Pro Garbage collected language
The language is garbage collected in two modes: reference counting or using the Boehm-Demers-Weiser conservative garbage collector.
Pro GUI for apps
BlitzMax provides the MaxGUI modules that allow to build GUI desktop applications for Windows, Mac and Linux (FLTK or GTK via a module). You also could create your own 'gadgets'.
Pro Great community support
the forum is plenty of examples and solutions! Community is strong and still working, available for getting an hand
Pro BLIde
BLIde is an integrated development environment for Blitz Max, designed to work very close to the project file management performed by BlitzMax engine.
It’s inspired by the .NET IDE and some other great tools, It’s been designed for hobbyist and professional coders.
Pro Easy to use
You'll need to put more time in learning Unity + Playmaker compared to something like GameSalad. But once get the hang of it and familiarize yourself with what it's possible to build with them, it's quite easy to use.
Pro Provides access to a huge list of assets through Asset Store
For those developers who can't afford an artist, or aren't skilled enough to create their own art, Unity features an Asset Store full of a wide variety of free and paid assets that can be easily added to your game. The Asset Store has more than just music and art. It also has code and modules that can be added to your game such as unique lighting or GUI systems.
Pro Third party plugins support
A lot of third party plugins have support for Playmaker. Playmaker team also invest time to add support for a lot of third party plugins.

Pro Elegant state-based visual scripting
Instead of a single "if this then that" event list which can become very cluttered beyond the most basic behaviors, PlayMaker gives each object a list of states where only certain events are triggered, and performing an action also changes state.
This allows for a clean, simple visual representation which helps break complex logical structures into smaller pieces, making them easier to understand.

Pro Powerful
It basically can do same things as scripting in Unity.
Cons
Con Outdated and abandoned
The author neglected BlitzMax and works on Monkey2.
Con No mobile targets
Only desktop targets available: Windows, MacOS, Linux.
Con Comparatively high learning curve
Although C#, JavaScript, and Boo have extensive documentation available online, it could still be difficult to wrap your head around the library and Unity's component based system.
Con Limited tutorials
There are not a lot videos with Playmaker tutorials. Official text tutorials are also quite limited. Even not every action has a description on an official wiki.
Con Performance could be better for 2D
Performance can be a real issue with 2D games. Unity 3D is actually a 3D game engine, and drags a lot of overhead with it.
For mobile, one could never achieve the performance of more specialized 2D engines with Unity3D.
