When comparing PlayMaker vs 2D Toolkit, the Slant community recommends 2D Toolkit for most people. In the question“What are the best Unity3D plug-ins?” 2D Toolkit is ranked 2nd while PlayMaker is ranked 3rd. The most important reason people chose 2D Toolkit is:
The documentation for the toolkit is well written and there are video tutorials as well as an active community.
Ranked in these QuestionsQuestion Ranking
Pros
Pro Easy to use
You'll need to put more time in learning Unity + Playmaker compared to something like GameSalad. But once get hang of it and familiarize yourself with it's possibilities. It's quite easy to use.
Pro Elegant state-based visual scripting
Instead of a single "if this then that" event list which can become very cluttered beyond the most basic behaviors, PlayMaker gives each object a list of states where only certain events are triggered, and performing an action also changes state.
This allows for a clean, simple visual representation which helps break complex logical structures into smaller pieces, making them easier to understand.
Pro Powerful
It basically can do same things as scripting in Unity.
Pro Third party plugins support
A lot of third party plugins have support for Playmaker. Playmaker team also invest time to add support for a lot of third party plugins.
Pro Good documentation
The documentation for the toolkit is well written and there are video tutorials as well as an active community.
Pro Includes source code
No need to pay more to get access to the source code.
Pro Pixel-perfect camera
Pixel games in the style of 8 or 16 bit systems need to have each pixel uniform on the screen which 2D Toolkit supports with a camera component.
Pro Add colliders in the atlas editor
Choose from either a box, sphere, or mesh collider that will output as either a 3D or 2D collider in Unity.
Pro Create different resolutions of atlas
2D Toolkit allows for different sizes of atlas from 1x, 2x, or 4x which can be changed depending on platform resolution.

Pro Built to work inside Unity
2D Toolkit is an editor extension so users don’t have to leave the Unity engine for tile mapping.

Pro Create Atlases within the tool
Create sprite sheets for tiles to save draw calls and to keep tilesets organized.

Pro Supports the Tiled TMX Format
Create tilemaps in Tiled and implement with 2D Toolkit.
Cons
Con Limited tutorials
There are not a lot videos with Playmaker tutorials. Official text tutorials are also quite limited. Even not every action has a description on an official wiki.

Con Doesn't integrate with Unity's Sprite system
2D Toolkit provides a completely proprietary sprite implementation. Though it can be used alongside Unity's 2D systems, the two are completely separate and require different code to utilize.
