When comparing Qt vs Sciter, the Slant community recommends Qt for most people. In the question“What are the best cross-platform GUI toolkits?” Qt is ranked 2nd while Sciter is ranked 19th.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Open-source
Pro Global community
The community behind Qt is both massive and approachable. Digia (also owners) are joined by the likes of Intel, KDAB, ICS, Canonical and numerous others in sponsoring development, while communities such as KDE also contribute significantly. Forums are active, mailing lists are open, irc channels chatting, git repositories well managed. Answers to questions are usually minutes away.
Pro Good documentation
Professional, thorough documentation with examples, available either in a web browser or in the stand-alone desktop client called assistant.
Pro Multi language
Support for C++, C#, Delphi, D, Go, Rust, Powerbuilder. See Go bindings on GitHub. The binding for C# on GitHub, SciterSharp does not seem to be free: in a commercial product you should acquire a commercial license.
Pro Lightweight
Only a single native DLL.
Cons
Con Linux version is not very mature
The Linux version is missing HTML/CSS features when compared to the Windows version.
Con Not fully HTML5 compliant
Lacking HTML5 functionality and W3C standards: grabbing a library like JQuery or Bootstrap and use it in Sciter will not work.
Con Not WYSIWYG
Not WYSIWYG like WebForms or WPF.