When comparing PyGObject / Python3 vs Lobster, the Slant community recommends Lobster for most people. In the question“What are the best languages to write a desktop Linux application in?” Lobster is ranked 11th while PyGObject / Python3 is ranked 18th. The most important reason people chose Lobster is:
Unlike Rust doesn't make the programmer jump through hoops, mainly automatic. Does an analysis similar to the Rust borrow checker to infer lifetimes, but makes life easier on the programmer.
Specs
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Pros
Pro Works particularly well on Linux, as many desktops use Python and GObject
GObject is a 'C' library with bindings to many other languages, so can be widely used.
Nice GTK.UIManager function to produce a menu system from a string.
Pro Compile time reference counting
Unlike Rust doesn't make the programmer jump through hoops, mainly automatic. Does an analysis similar to the Rust borrow checker to infer lifetimes, but makes life easier on the programmer.
Pro Python-esque syntax
There's an audience who loves that.
Pro WebAssembly backend
More options for users.
Pro Inline structs
Structs are allocated in their parent, and come at zero overhead.
Pro Automatic memory management
Better than Rust. No sadism.
Pro Type inference algorithm
Just works. Goes further than most languages in terms of allowing code without types.
Cons
Con Doesn't work well if you're targetting Windows, even though there probably is a binding
Not very close to Windows look and feel.
Con Small community
Lead doesn't appear to be so ambitious or has a vision to push making more popular.
Con Compile time reference counting not 100%
Around 5% of time, need to escape to runtime reference counting. Working to get the percentage as low as possible.
Con Lobster not yet totally written in Lobster
Core written in C++. Plans to change that, but has been a long time.
Con Python-like syntax, but different use case and domain
Not Python compatible and often significantly different in purpose and use cases.