When comparing GRPC vs Pyramid, the Slant community recommends Pyramid for most people. In the question“What are the best backend web frameworks?” Pyramid is ranked 15th while GRPC is ranked 53rd. The most important reason people chose Pyramid is:
Pyramid can be used for creating small applications quickly and easily, but it also powers up large enterprise-scale applications such as Dropbox.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Allows streaming
Streaming can not be done with a REST API, read Unary Streaming via gRPC.
Pro Cross platform
Pro Super fast
Pro Very flexible
Pyramid can be used for creating small applications quickly and easily, but it also powers up large enterprise-scale applications such as Dropbox.
Pro Persistence agnostic
Either NoSQL and SQL (including SQLAlchemy plugin).
Pro Comes with security included
Includes authorization and authentication with multiple backends.
Cons
Con The great number of options it offers can become intimidating
One of Pyramid's greatest drawbacks is that it requires a lot of set up in the beginning of a project. This can feel overwhelming and can keep people away from using it.