When comparing DEVONthink vs Dendron, the Slant community recommends Dendron for most people. In the question“What are the best knowledge base systems for personal use?” Dendron is ranked 18th while DEVONthink is ranked 25th. The most important reason people chose Dendron is:
Dendron does not pull notes off your system unless you want to explicitly. There are easy guides for syncing with Github or you can always use Dropbox, Onedrive etc. to sync your notes wherever you want.
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Pros
Pro Can store any file type
File types containing text are indexed.
Pro Very flexible
An extensive feature set makes it easy to adapt to your work flow.
Pro Completely offline
Pro Sync
Sync between different macs and/or ios devices is fast, safe and easy. You can sync via iCloud, Dropbox, WebDAV or WiFi.
Pro Full text search
Pro Webpage Clipper
A flexible web clipper can add contents of any web page to DevonThink.
Pro One-time purchase vs monthly subscription.
Pro Paperless office functions available in PRO Office version
Includes processing of scanned documents, OCR etc.
The OCR function is based on FineReader and is probably the best one on the market.
Pro Local-first
Dendron does not pull notes off your system unless you want to explicitly. There are easy guides for syncing with Github or you can always use Dropbox, Onedrive etc. to sync your notes wherever you want.
Pro Open-source
Pro Built into VSCode
If you're already developing in VSCode, it's great to have your notes in a familiar environment. Reduces switching costs and you can use familiar keybindings.
Pro Flexible hierarchies
Dendron makes it easy to create and refactor hierarchies at will.
Pro Powerful built-in publishing
Dendron ships with a configuration for publishing your notes with Next.js. The resulting site is searchable and easy to navigate, and the VS Code extension can easily place links to notes in your clipboard for rapid sharing.
Pro It works the way your brain works
You can literally just start writing; Dendron doesn't force you into bullets, folders, projects, etc. You build your vault the way you want it, and Dendron takes care of the presentation.
Pro Helpful development team
Dendron's developers are always putting out videos and office hours to help others become familiar with Dendron.
Cons
Con Only runs on Macs, iPoneOS, iPadOS & Web
It does not run on Windows, Android, and Linux.
Con Stores in a proprietary format
It stores the whole database in a proprietary file package, that you cannot easily access from another app or from the Finder. Considering you might be classifying a huge quantity of files there, it is quite problematic if you want to interact with this data from other applications.
Con Very limited automation
While the marketing claims are about an intelligent document manager, it actually does not offer many automation features, such as automatic classification, tagging and renaming of the files. It's much more like an extended file explorer.
Con Costs US$79.95 for just the Personal version
One-time purchase instead of monthly subscription.
Con Non free/libre (proprietary)
Con Little bit of a learning curve
If you're not familiar with VSCode, there may be a steep learning curve.
Con No mobile app
Dendron runs in VSCode so no ou-of-the-box mobile sync/experience.
