When comparing SmoothMoves vs Moho 12, the Slant community recommends Moho 12 for most people. In the question“What are the best 2D skeletal animation tools?” Moho 12 is ranked 7th while SmoothMoves is ranked 12th. The most important reason people chose Moho 12 is:
Cheaper than Toon Boom and Adobe Products. People often complain about the price hike, but the pro version does go on sale, and even the full priced version is less than other insdurty standards on the market.
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Pros

Pro PlayMaker integration
Developers echo17 provide Playmaker action scripts for SmoothMoves.

Pro Texture swapping and tinting at runtime
Animations can be re-skinned in several ways, entirely on the fly.
Pro Cheaper than Toon Boom and Adobe Products
Cheaper than Toon Boom and Adobe Products. People often complain about the price hike, but the pro version does go on sale, and even the full priced version is less than other insdurty standards on the market.
Pro Good community support
Lots of online forums, Facebook groups, YouTube videos, etc.
Pro It's better than any 2D animation software on the market for vector based animations
It beats Adobe Flash and Toon Boom at vector based animation. It has more features for 2D vector animations with it's integration with 3D mesh and bone rigs. Smart bone rigs create better animtions with less distortions then Toon Boom, and there are no bone rig animation options with Adobe Flash.
Pro Easy to use interface
Quicker to animate and use than other similar products.
Cons

Con Bone hierarchy is not collapsible
When working with a complex skeleton, the entire tree is always visible. There is no way to hide bones under their parents.

Con Unity Middleware
SmoothMoves is not a stand-alone application. It runs entirely within the Unity Editor, and is not compatible with other engines.
Con Too expensive
Con Limited support for game engines
In most cases you'll have to export and edit sprite sheets. This will consume memory. Also, FBX file support is limited and not all features will run in Unity. Aside from Unity, there is no support for runtimes for video game engines. Also, many animation features such as vector integrated features will not export to Unity. Spriter, Spine, and Dragon Bones would be better options.
