When comparing Cocos2d-x and Cocos Creator vs PlayMaker + Unity3D, the Slant community recommends Cocos2d-x and Cocos Creator for most people. In the question“What are the best 2D game engines?” Cocos2d-x and Cocos Creator is ranked 10th while PlayMaker + Unity3D is ranked 77th. The most important reason people chose Cocos2d-x and Cocos Creator is:
25% of iPhone games are made using Cocos2d-x. This means you will not be alone in development, and will have access to a large community. You'll know you are developing for an engine that works.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro A proven engine for mobile development
25% of iPhone games are made using Cocos2d-x.
This means you will not be alone in development, and will have access to a large community. You'll know you are developing for an engine that works.

Pro Good documentation
Documentation includes a programming guide, API reference, video tutorials and massive reference test code project showing all functions and giving working code to the user.

Pro Supports 3D models with skeleton animation
A new feature since Cocos2d-x v3.1 is support for 3D models (in your 2D game), not only this but support for skeleton animations is included too! This awesome feature allows for impressive characters in your game along with easier, more fluid and realistic animations.
Pro Great script language support
It supports Lua and Javascript with full feature support.
Especially with Cocos2d-JS you can develop games cross web and native, and the native solution have great performance with JS Bindings, much better than hybrid solution.

Pro Highly active community for questions and support
Cocos2d-x forums are active.
Pro OpenGL hardware acceleration

Pro Future-proof
Cocos2d-x is not only open source but also supported by Chukong Technologies of China and USA.
Regularly updated and adding support for the latest technologies. 2014 has already seen the release of Version 3, a new Cocos Studio development toolkit (optional) and support for new technologies like skeleton animation systems Spine and Adobe DragonBone.
Pro Greater performance than high level APIs
Cocos2d-x is C++ based engine and it has CPU advantages for most platforms because of that. It uses polygonal mesh methods for sprite rendering for using GPU advantages. (You also use quad methods for benefit CPU).
Pro No external dependencies
Because it is based on Pyglet.
Pro One code for all platforms
On top of supporting pretty much all existing platforms (except consoles), Cocos Creator (Cocos's IDE) allows you to write 1 code that runs on Android, iOS, Windows, MacOS and HTML5 (not Linux though).
Pro Easy integration of 3rd party plugins
Through the use of SDKBox you can easily integrate 3rd party SDKs and plugins for each version of Cocos2D (Lua, C++ or JavaScript), you just choose the SDKs to integrate and SDKBox will do the rest.
For example, if you want to add a rating plugin, you use sdkbox::PluginReview::init();
and if you want to add the Vundle Ad Network SDK, you use the one packaged in SDKBox SDKBOX sdkbox::PluginVungle::init();
.
Pro Allows for easy debugging
It has a built-in Python interpreter that allows for easy debugging.
Pro Very good IDE
Cocos Creator (Cocos' IDE) comes with scene editing, UI editor, animations & particle editors and whatnot. It's also easy to use and pretty intuitive if you read the official documentation & tutorials. Way way better than the old CocoStudio.
Pro Great video tutorials
Hundreds of video tutorials available.
Pro Easy to use
You'll need to put more time in learning Unity + Playmaker compared to something like GameSalad. But once get the hang of it and familiarize yourself with what it's possible to build with them, it's quite easy to use.
Pro Provides access to a huge list of assets through Asset Store
For those developers who can't afford an artist, or aren't skilled enough to create their own art, Unity features an Asset Store full of a wide variety of free and paid assets that can be easily added to your game. The Asset Store has more than just music and art. It also has code and modules that can be added to your game such as unique lighting or GUI systems.
Pro Third party plugins support
A lot of third party plugins have support for Playmaker. Playmaker team also invest time to add support for a lot of third party plugins.

Pro Elegant state-based visual scripting
Instead of a single "if this then that" event list which can become very cluttered beyond the most basic behaviors, PlayMaker gives each object a list of states where only certain events are triggered, and performing an action also changes state.
This allows for a clean, simple visual representation which helps break complex logical structures into smaller pieces, making them easier to understand.

Pro Powerful
It basically can do same things as scripting in Unity.
Cons
Con Poor support and non-existent community
Up until 2013, this was one of the best engines around. However, since then it was bought by a Chinese company and began stagnating - it's virtually in a slow death. Most developers abandoned Cocos in favor of more modern solutions leaving the community weak and the forums with little or no traffic. Although the Cocos2d-x Forum seems to have a decent community going.
Con No Graphics user interface
Con Modest functionality
Almost all free alternatives are more convenient, faster, and more functional.
Con Comparatively high learning curve
Although C#, JavaScript, and Boo have extensive documentation available online, it could still be difficult to wrap your head around the library and Unity's component based system.
Con Limited tutorials
There are not a lot videos with Playmaker tutorials. Official text tutorials are also quite limited. Even not every action has a description on an official wiki.
Con Performance could be better for 2D
Performance can be a real issue with 2D games. Unity 3D is actually a 3D game engine, and drags a lot of overhead with it.
For mobile, one could never achieve the performance of more specialized 2D engines with Unity3D.
